Professor

　　　　State Key Laboratory of Systematic and Evolutionary Botany

　　　　Institute of Botany

　　　　Chinese Academy of Sciences

　　　　Beijing 100093, China

　　　　Email: yalong.guo@ibcas.ac.cn 

　　　　Education

　　　　2005 - 2011 Postdoctoral Fellow in plant genomics and genetics, Max-Planck Institute for Developmental Biology, Tübingen, Germany.

　　2001 - 2005 Ph.D. in plant systematics and evolution - “Molecular systematics of the tribe Oryzeae (Poaceae)”, Institute of Botany, Chinese Academy of Sciences, China.

　　1998 - 2001 M.S. in plant physiology - “Metabolism of reactive oxygen species under natural drought stress in wheat strains”, Lanzhou University, China.

　　1994 - 1998 B.A., Undergraduate studies in biology, Northwest Normal University, China.

　　　　Professional experience

　　2011 - present Professor, State Key Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences, Beijing, China.

　　　　Research interests

　　　　Our research interests include three areas, evolutionary genomics, speciation and evolution of self-incompatibility systems, and natural variation and adaptation. The plant species we study include but not limited to the dicot model species, Arabidopsis thaliana, and related species in the Brassicaceae and the monocot model species, rice (Oryza sativa), and its relatives.

　　　　Publications （§ co-first author, * correspondence author）

　　　　Ge S*, Guo YL. 2020. Evolution of genes and genomes in the genomics era. Science China Life Science 63: 602-605.

　　　　Zhang MX, Zhu SS, Xu YC, Guo YL, Yang WC*, Li HJ*. 2020. Transcriptional repression specifies the central cell for double fertilization. Proc Natl Acad Sci U S A 117: 6231-6236.

　　　　Zhang J, Fu XX, Li RQ, Zhao X, Liu Y, Li MH, Zwaenepoel A, Ma H, Goffinet B, Guan YL, Xue JY, Liao YY, Wang QF, Wang QH, Wang JY, Zhang GQ, Wang ZW, Jia Y, Wang MZ, Dong SS, Yang JF, Jiao YN, Guo YL, Kong HZ, Lu AM, Yang HM, Zhang SZ*, Van de Peer Y*, Liu ZJ*, Chen ZD*. 2020. The hornwort genome and early land plant evolution. Nature Plants 6: 107-118.

　　　　Niu XM§, Xu YC§, Li ZW, Bian YT, Hou XH, Chen JF, Zou YP, Jiang J, Wu Q, Ge S, Balasubramanian S, Guo YL*. 2019. Transposable elements drive rapid phenotypic variation in Capsella rubella. Proc Natl Acad Sci U S A 116: 6908-6913. (Cover story)

　　　　Zhong S, Liu M, Wang Z, Huang Q, Hou S, Xu YC, Ge Z, Song Z, Huang J, Qiu X, Shi Y, Xiao J, Liu P, Guo YL, Dong J, Dresselhaus T, Gu H, Qu LJ*. 2019. Cysteine-rich peptides promote interspecific genetic isolation in Arabidopsis. Science 364, 851.

　　　　Xu YC, Niu XM, Li XX, He W, Chen JF, Zou YP, Wu Q, Zhang YE, Busch W, Guo YL*. 2019. Adaptation and phenotypic diversification through loss-of-function mutations in Arabidopsis protein-coding genes. Plant Cell 31: 1012-1025.

　　[For perspectives on this work, see: 1] Caseys C. 2019. Loss-of-function, a strategy for adaptation in Arabidopsis. Plant Cell 31: 935. 2] Faculty of 1000 Biology: https://f1000.com/prime/735346397]

　　　　Li Z, Mo W, Jia L, Xu YC, Tang W, Yang W, Guo YL, Lin R*. 2019. Rice FLUORESCENT1 is involved in the regulation of chlorophyll. Plant Cell Physiol 60: 2307-2318.

　　　　Cai Z, Zhou L, Ren NN, Xu X, Liu R, Huang L, Zheng XM, Meng QL, Du YS, Wang MX, Geng MF, Chen WL, Jing CY, Zou XH, Guo J, Chen CB, Zeng HZ, Liang YT, Wei XH, Guo YL, Zhou HF, Zhang FM, Ge S*. 2019. Parallel speciation of wild rice associated with habitat shifts. Mol Biol Evol 31: 875-889.

　　　　郭亚龙*. 2019. 拟南芥及其近缘种的适应性进化研究. 中国科学：生命科学 49: 320-326.

　　　　Yan Z, Hou X, Han W, Ma S, Shen H, Guo YL, Fang J*. 2019. Effects of nitrogen and phosphorus supply on stoichiometry of six elements in leaves of Arabidopsis thaliana. Annals of Botany 123: 441-450.

　　　　Mao D, Xin Y, Tan Y, Hu X, Bai J, Liu ZY, Yu Y, Li L, Peng C, Fan T, Zhu Y, Guo YL, Wang S, Lu D, Xing Y, Yuan L*, Chen C*. 2019. Natural variation in the HAN1 gene confers chilling tolerance in rice and allowed adaptation to a temperate climate. Proc Natl Acad Sci U S A 116: 3494-3501.

　　　　Yang L§, Wang HN§, Hou XH, Zou YP, Han TS, Niu XM, Zhang J, Zhao Z, Todesco M, Balasubramanian S, Guo YL*. 2018. Parallel evolution of common allelic variants confers flowering diversity in Capsella rubella. Plant Cell 30: 1322-1336.

　　[For perspectives on this work, see: 1) Moyers BT. 2018. Is Genetic Evolution Predictable? Plant Cell 30: 1171-1172. 2) Faculty of 1000 Biology: https://f1000.com/prime/733248611#]

　　　　Shen Y, Zhang J, Liu Y, Liu S, Liu Z, Duan Z, Wang Z, Zhu B, Guo YL, Tian Z*. 2018. DNA methylation footprints during soybean domestication and improvement. Genome Biology 19: 128.

　　　　Li ZW§, Hou XH§, Chen JF, Xu YC, Wu Q, González J, Guo YL*. 2018. Transposable elements contribute to the adaptation of Arabidopsis thaliana. Genome Biology and Evolution 10: 2140-2150.

　　　　Yan Z, Li X, Tian D, Han W, Hou X, Shen H, Guo YL, Fang J*. 2018. Nutrient addition affects scaling relationship of leaf nitrogen to phosphorus in Arabidopsis thaliana. Functional Ecology 32: 2689-2698.

　　　　Zou YP§, Hou XH§, Wu Q, Chen JF, Li ZW, Han TS, Niu XM, Yang L, Xu YC, Zhang J, Zhang FM, Tan D, Tian Z, Gu H, Guo YL*. 2017. Adaptation of Arabidopsis thaliana to the Yangtze River basin. Genome Biology 18: 239.

　　　　Wu Q, Han TS, Chen X, Chen JF, Zou YP, Li ZW, Xu YC, Guo YL*. 2017. Long-term balancing selection contributes to adaptation in Arabidopsis and its relatives. Genome Biology 18: 217.

　　[For a perspective on this work, see: Wang B, Mitchell-Olds T. 2017. Balancing selection and trans-specific polymorphisms. Genome Biology 18: 231]

　　　　Li W, Zhang F, Wu R, Jia L, Li G, Guo YL, Liu C, Wang G*. 2017. A novel N-methyltransferase in Arabidopsis appears to feed a conserved pathway for nicotinate detoxification among land plants and is associated with lignin biosynthesis. Plant Physiology 174: 1492-1504.

　　　　Li ZW, Chen X, Wu Q, Hagmann J, Han TS, Zou YP, Ge S, Guo YL*. 2016. On the origin of de novo genes in Arabidopsis thaliana populations. Genome Biology and Evolution 8: 2190-2202.

　　　　Yan Z, Guan H, Han W, Han TS, Guo YL, Fang J*. 2016. Reproductive organ and young tissues show constrained elemental composition in Arabidopsis thaliana. Annals of Botany 117: 431-439.

　　　　Han TS, Wu Q, Hou XH, Li ZW, Zou YP, Ge S, Guo YL*. 2015. Frequent introgressions from diploid species contribute to the adaptation of the tetraploid Shepherd’s purse (Capsella bursa-pastoris). Molecular Plant 8: 427-438. (Cover story)

　　　　Yan Z, Kim N, Han W, Guo YL, Han TS, Du E, Fang J*. 2015. Effects of nitrogen and phosphorus supply on growth rate, leaf stoichiometry, and nutrient resorption of Arabidopsis thaliana. Plant Soil 388: 147-155.

　　　　Slotte T, Hazzouri KM, Agren JA, Koenig D, Maumus F, Guo YL, Steige K, Platts AE, Escobar JS, Newman LK, Wang W, Mandáková T, Vello E, Smith LM, Henz SR, Steffen J, Takuno S, Brandvain Y, Coop G, Andolfatto P, Hu TT, Blanchette M, Clark RM, Quesneville H, Nordborg M, Gaut BS, Lysak MA, Jenkins J, Grimwood J, Chapman J, Prochnik S, Shu S, Rokhsar D, Schmutz J, Weigel D*, Wright SI*. 2013. The Capsella rubella genome and the genomic consequences of rapid mating system evolution. Nature Genetics 45: 831-835.

　　　　Guo YL*. 2013. Gene family evolution in green plants with emphasis on the origination and evolution of Arabidopsis thaliana genes. Plant Journal 73: 941-951.

　　　　Guo YL, Todesco M, Hagmann J, Das S, Weigel D*. 2012. Independent FLC mutations as causes of flowering time variation in Arabidopsis thaliana and Capsella rubella. Genetics 192: 729-739.

　　　　Guo YL, Fitz J, Schneeberger K, Ossowski S, Cao J, Weigel D*. 2011. Genome-wide comparison of NB-LRR encoding resistance genes in Arabidopsis. Plant Physiology 157: 757-769.

　　　　Guo YL§*, Zhao X§, Lanz C, Weigel D. 2011. Evolution of S-locus region in Arabidopsis thaliana relatives. Plant Physiology 157: 937-946.

　　　　Hu TT§, Pattyn P§, Bakker EG, Cao J, Cheng JF, Clark RM, Fahlgren N, Fawcett JA, Grimwood J, Gundlach H, Haberer G, Hollister JD, Ossowski S, Ottilar RP, Salamov A, Schneeberger K, Spannagl M, Wang X, Yang L, Nasrallah ME, Bergelson J, Carrington JC, Gaut BS, Schmutz J, Mayer KFX, Van De Peer Y, Grigoriev IV, Nordborg M, Weigel D*, Guo YL*. 2011. The Arabidopsis lyrata genome sequence and the basis of rapid genome size change. Nature Genetics 43: 476-481.

　　　　Hollister JD, Smith LM, Guo YL, Ott F, Weigel D*, Gaut BS*. 2011. Transposable elements and small RNAs contribute to gene expression divergence between Arabidopsis thaliana and Arabidopsis lyrata. Proc. Natl. Acad. Sci. USA 108: 2322-2327.

　　　　Wahl V, Brand LH, Guo YL, Schmid M*. 2010. The FANTASTIC FOUR proteins influence shoot meristem size in Arabidopsis thaliana. BMC Plant Biology 10: 285.

　　　　Guo YL§, Bechsgaard JS§, Slotte T, Neuffer B, Lascoux M, Weigel D*, Schierup MH*. 2009. Recent speciation of Capsella rubella from C. grandiflora, associated with loss of self-incompatibility and an extreme bottleneck. Proc. Natl. Acad. Sci. USA 106: 5246-5251.

　　[For perspectives on this work, see: 1) Pannell JR. 2009. Mating-system evolution: genies from a bottleneck. Current Biology 19(9): R369-R370. 2) Faculty of 1000 Biology: http://f1000.com/1158981]

　　　　Tang C, Toomajian C, Sherman-Broyles S, Plagnol V, Guo YL, Hu TT, Clark RM, Nasrallah JB, Weigel D, Nordborg M*. 2007. The evolution of selfing in Arabidopsis thaliana. Science 317: 1070-1072.

　　[For a perspective on this work, see Faculty of 1000 Biology: http://f1000.com/1089382]

　　　　Guo YL, Ge S*. 2006. Advances in the study of systematics and evolution of the tribe Oryzeae (Poaceae). Acta Phytotaxonomica Sinica 44: 211-230.

　　　　Guo YL, Ge S*. 2005. Molecular phylogeny of Oryzeae (Poaceae) based on DNA sequences from chloroplast, mitochondrial and nuclear genomes. American Journal of Botany 92: 1548-1558.

　　[For a perspective on this work, see Faculty of 1000 Biology: http://f1000.com/1029056]

　　　　Guo YL, Ge S*. 2004. The utility of mitochondrial nad1 intron in phylogenetic study of Oryzeae with reference to the systematic position of Porteresia. Acta Phytotaxonomica Sinica 42: 333-344.